Manuscripts published in JACC Journals were among the most talked about in cardiology last year. Among the top articles was The Association of Frailty With In-Hospital Bleeding Among Older Adults With Acute Myocardial Infarction, published in JACC: Cardiovascular Interventions. According to the study, increasing frailty in acute myocardial infarction patients ages 65 and older may be associated with major bleeding overall, and these patients may be at increased risk of bleeding when undergoing cardiac catherization. Read more. View the full list of articles published in JACC and JACC specialty journals that received the most media and social media attention throughout the world last year.