The latest issue of JACC: Advances includes a state-of-the-art review on catheter-based interventions for the management of valvular heart disease during pregnancy and research dedicated to filling the gap in data for older patients with nonvalvular atrial fibrillation and reduced dosing of direct-acting oral anticoagulants. Covering a range of new and emerging cardiovascular fields, the issue includes research examining mid-life cardiorespiratory fitness, obesity and risk of atrial fibrillation, long-term benefits of tricuspid valve replacement, optimal perfusion targets in cardiogenic shock, and more. In addition, a viewpoint by Thomas M. Das, MD, et al., looks at medical education in the digital era and how learning is in synergy with both digital and traditional curricula. Finally, in the Editor's Page, Editor-in-Chief Candice K. Silversides, MD, and Deputy Editor David R. Holmes Jr., MD, MACC, outline the importance of the multidisciplinary heart team in managing complex cardiac patients. Read the full issue and listen to an issue summary podcast recorded by Silversides. To stay up to date, opt in receive eTable of Contents emails for future issues of JACC: Advances and follow the JACC family of Journals on social media.