In a recent Cardiology article, Peter C. Block, MD, FACC, focuses on a central question: how does CAD relate to myocardial ischemia? He notes that if a stable mid-coronary lesion is present, perhaps the real site of action is all downstream.

Can a proximal atherosclerotic plaque affect the distal arterioles that nourish the myocardium? Even so, if PCI changes the plaque, why does that not change mortality? Read more.

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