The ACC and the American Heart Association have released a focused update of guidelines for the treatment of patients with valvular heart disease. The new guidance, which has been updated to reflect the latest research since the last guidelines were published in 2014, was published March 15 in the Journal of the American College of Cardiology. Specifically, the focused update includes changes in indications for antibiotic prophylaxis for infective endocarditis, the use of direct oral anticoagulants among patients with atrial fibrillation and heart valve disease, indications for transcatheter aortic valve replacement, surgical management of patients with primary and secondary mitral regurgitation, and management of patients with a heart valve prosthesis. Read more on ACC.org.