JACC: CardioOncology has published a special focus issue dedicated to immune therapy. Articles include a state-of-the-art review on cancer immunotherapy beyond checkpoint blockade; current uses and future directions of immune checkpoint inhibitor therapy in oncology; atherosclerosis with immune checkpoint inhibitor therapy; and more. "While we recognize that actionable science and our clinical experiences are continuously formulated, we hope that this issue will serve as your go-to resource as we seek to motivate evidence-based, empathic care for our patients and stimulate new science to advance cardiovascular and oncologic health," said Bonnie Ky, MD, FACC, editor-in-chief of JACC: CardioOncology. Read the full issue.