ACC CardiaCast: Women are Not Little Men: Underrepresentation of Women in Clinical Research and Trials

“Women are Not Little Men” is a new podcast series within CardiaCast designed for cardiovascular health providers to increase awareness of sex-based differences in cardiovascular disease (CVD) and to improve the clinical care of women with CVD. “Women are Not Little Men” is hosted by Drs. Emily Lau and Niti Aggarwal, nationally renowned experts in women’s CVD and members of the American College of Cardiology CVD in Women Committee. In this episode, Drs. Leslie Cho and Michelle O’Donoghue review the landscape of sex and gender representation in cardiovascular clinical research and trials, implications for translation of research to clinical care for women, and strategies for improving female representation.

Related References:

  1. Cho L, Vest A, O’Donoghue M, et al; Cardiovascular Disease in Women Committee Leadership Council. Increasing participation of women in cardiovascular trials. J Am Coll Cardiol 2021;78:737–51.
  2. Lau ES, Braunwald E, Morrow DA, et al. Sex, permanent drug discontinuation, and study retention in clinical trials. Circulation 2021;143:685-95.
  3. Walsh MN. Gender diversity in cardiovascular clinical trial research begins at the top. J Am Coll Cardiol 2022;79:929–32.




Clinical Topics: Acute Coronary Syndromes, Anticoagulation Management, Heart Failure and Cardiomyopathies, Prevention, Stable Ischemic Heart Disease, Valvular Heart Disease

Keywords: CardiaCast, Clinical Trials as Topic, Women


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