Colchicine in Acute Coronary Syndrome: When to Commence?

Sep 15, 2021   |  Aernoud Fiolet; Tjerk Simon Jacob Opstal, MD; Peter Thompson, MD; Jan Hein Cornel

Expert Analysis

Patients with coronary disease have a life-long increased risk of developing new major adverse cardiovascular events.

Clinical Topics: Acute Coronary Syndromes, Arrhythmias and Clinical EP, Cardiovascular Care Team, Noninvasive Imaging, Pericardial Disease, Prevention, ACS and Cardiac Biomarkers, Implantable Devices, SCD/Ventricular Arrhythmias, Atrial Fibrillation/Supraventricular Arrhythmias, Magnetic Resonance Imaging

Keywords: Colchicum, Troponin T, Interleukin-6, Inflammasomes, C-Reactive Protein, Leucine, Colchicine, Secondary Prevention, Cardiovascular Diseases, Acute Coronary Syndrome, Atrial Fibrillation, Familial Mediterranean Fever, Cytokines, Pharmaceutical Preparations, Neutrophil Infiltration, Biological Availability, Risk, Pyrin Domain, Confidence Intervals, Thoracotomy, Brain Ischemia, Neutrophils, Time, Stroke, Myocardial Infarction, Anti-Inflammatory Agents, Atherosclerosis, Coronary Disease, Thrombosis, Magnetic Resonance Imaging, Ischemia, Pericarditis, Cytoskeleton, Microtubules, Infarction, Reperfusion Injury, Regression Analysis, Hospitalization, Renal Insufficiency, Ambulatory Care Facilities, Ischemic Stroke, Ischemic Stroke, Creatine Kinase, Heart Arrest, Nucleotides, Biological Products

Efficacy and Safety of Colchicine in Patients With Chronic Stable Coronary Disease

Oct 30, 2020   |  Stefan M. Nidorf, MD, FACC; Peter Thompson, MD

Expert Analysis

Patients with coronary disease have a life-long risk of cardiovascular death, MI, and ischemic stroke and the need for coronary intervention due to progressive angina despite the aggressive use of lipid-lowering and antithrombotic therapy.

Clinical Topics: Acute Coronary Syndromes, Dyslipidemia, Prevention, Stable Ischemic Heart Disease, ACS and Cardiac Biomarkers, Nonstatins, Novel Agents, Statins, Chronic Angina

Keywords: Angina, Stable, Hydroxymethylglutaryl-CoA Reductase Inhibitors, C-Reactive Protein, Plaque, Atherosclerotic, Colchicine, Interleukin-1beta, Acute Coronary Syndrome, Clarithromycin, Antifungal Agents, Tubulin, Creatinine, Fibrinolytic Agents, Platelet Aggregation Inhibitors, Secondary Prevention