Elevated Lipoprotein(a) in Familial Hypercholesterolemia and its Role in the Progression of Calcific Aortic Stenosis

Apr 05, 2021   |  Nathan Bekele, MD; Molly Szerlip, MD, FACC; Anandita Kulkarni, MD, FACC

Expert Analysis

Aortic stenosis (AS) is one of the most prevalent forms of cardiovascular pathology in the western world, ranking only behind hypertension and coronary artery disease (CAD).

Clinical Topics: Anticoagulation Management, Cardiovascular Care Team, Dyslipidemia, Noninvasive Imaging, Prevention, Valvular Heart Disease, Atherosclerotic Disease (CAD/PAD), Advanced Lipid Testing, Lipid Metabolism, Nonstatins, Novel Agents, Primary Hyperlipidemia, Statins, Echocardiography/Ultrasound, Hypertension

Keywords: Primary Prevention, Cholesterol, LDL, PCSK9 protein, human, Proprotein Convertase 9, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Fibrinolysin, Niacin, Hyperlipoproteinemia Type II, Coronary Artery Disease, Aortic Valve, Arcus Senilis, Apolipoprotein A-II, American Heart Association, Plasminogen, Lipid Metabolism, Constriction, Pathologic, Genetic Predisposition to Disease, Phospholipids, Fibrin, Cardiovascular Diseases, Antifibrinolytic Agents, Follow-Up Studies, Goals, Mendelian Randomization Analysis, Receptors, LDL, Atherosclerosis, Heart Valve Diseases, Genetic Testing, Risk Factors, Hypertension, Lipoprotein(a), Thrombosis, Tunica Intima, Aortic Valve Stenosis, Physical Examination, Xanthomatosis, Asymptomatic Diseases, Echocardiography, Disease Progression, Wound Healing, Plasma, Diagnostic Techniques and Procedures, Subtilisins, Tendons